Iba1 (AIF1) Mouse Monoclonal Antibody [Clone ID: 1022-5]

Specifications

Product Data
Clone Name	1022-5
Applications	IHC
Recommend Dilution	Immunohistochemistry on Paraffin Sections: 5 µg/ml (1/40). Pretreatment is not necessary. Suggested Positive Control: Human spleen. This antibody does not react on routinely processed Frozen Sections.
Reactivity	Human, Rat, Porcine
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified Human recombinant AIF-1 Epitope is not further characterized.
Specificity	Recognizes AIF-1. This antibody BM4114B reacts with activated Macrophages / Microglial cells.
Formulation	PBS containing 5 mg/ml BSA as a stabilizer and 0.09% Sodium Azide as a preservative. Label: Biotin State: Lyophilized purified IgG fraction.
Reconstitution Method	Restore by adding 0.5 ml distilled water.
Concentration	0.2 mg/ml
Purification	Affinity Chromatography.
Conjugation	Biotin
Storage Condition	Store the original vial at 2-8°C, stock solution or aliquots thereof at -20°C. Avoid repeated thawing and freezing.
Gene Name	allograft inflammatory factor 1
Database Link	Entrez Gene 199 Human UniProt ID P55008
Background	Allograft Inflammatory Factor-1 is a Ca2+-binding peptide produced by activated macrophages and microglial cells. It has been suggested that AIF-1 expression is associated with chronic inflammatory processes. AIF-1, like the Ca2+-binding peptides MRP8 and MRP14, is expressed by activated macrophages and might participate in a variety of pathogenic processes in the mammalian brain and in chronic transplant rejection. It has been shown to be expressed early and persistently in chronically rejecting cardiac allografts but not in cardiac syngrafts and host hearts. The recently described apoptosis-inducing factor AIF is not related to AIF-1.
Synonyms	AIF-1, Protein G1, IBA1, Allograft inflammatory factor 1
Reference Data

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