Insulin (INS) Mouse Monoclonal Antibody [Clone ID: E6-E5 (7F8)]

Specifications

Product Data
Clone Name	E6-E5 (7F8)
Applications	ELISA
Recommend Dilution	ELISA: BM505 is suitable for use as Coating antibody in a Sandwich ELISA with AM02306PU-N as the Detection antibody.
Reactivity	Bovine, Human, Porcine
Host	Mouse
Clonality	Monoclonal
Immunogen	Human Insulin.
Specificity	BM505 recognizes Insulin, a major metabolic hormone produced by B cells of the pancreas.
Formulation	PBS containing 0.09% Sodium Azide as preservative State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	insulin
Database Link	Entrez Gene 3630 Human UniProt ID P01308
Background	Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B cell origin such as insulinoma.
Synonyms	INS
Reference Data

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