Neurofilament (NEFM) Mouse Monoclonal Antibody [Clone ID: NF403]

Specifications

Product Data
Clone Name	NF403
Applications	IHC, WB
Recommend Dilution	Immunohistochemistry on Frozen and Paraffin Sections: 1/10 for 1 h at room temperature. Recommended Positive Control: Human brain tissue. Immunoblotting. Cell preparations.
Reactivity	Bovine, Guinea Pig, Human, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Neurofilament preparation isolated from calf brain tissue.
Specificity	Marker for the differentiation of 160 kD neurofilament peptide from other intermediate filament proteins. The antibody is useful for studying neurofilament expression and for tumor characterization (pheochromocytoma, paraganglioma, ganglioneuroblastoma, ganglioneuroma and other tumors of neuronal origin).
Formulation	State: Supernatant State: Liquid Culture Supernatant containing 0.09% Sodium Azide as preservative.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	neurofilament, medium polypeptide
Database Link	Entrez Gene 4741 Human UniProt ID P07197
Background	Neurofilaments can be defined as the intermediate or 10nm diameter filaments found in neuronal cells. They are composed a mixture of subunits which often includes the neurofilament triplet proteins, NF-L, NF-M and NF-H. Neurofilaments may also include peripherin, alpha-internexin, nestin and in some cases vimentin. Antibodies to the various neurofilament subunits are very useful cell type markers since the proteins are quite abundant, biochemically stable. This antibody was raised against the C-terminal region of NF-M, a region highly conserved between NF-M molecules in different species. Accordingly the antibody recognizes all mammalian and avian NF-M molecules. The name NF-M refers to the fact that this is the "middle" or "medium" protein of neurofilament triplet, the other two proteins being "low" or "light" (NF-L) and "high" or "heavy" (NF-H). NF-M is sometimes also referred to as NEF3 or Neurofilament
Synonyms	Neurofilament medium polypeptide, NF-M, NEF3, NEFM, Neurofilament 3, (Neuronal Marker)
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.