Lipoprotein lipase (LPL) Mouse Monoclonal Antibody [Clone ID: Mab-7]

Specifications

Product Data
Clone Name	Mab-7
Applications	ELISA, FN, IHC, WB
Recommend Dilution	ELISA. Immunoblotting. Immunohistochemistry. Recommended Dilutions: 1/10. Dilution buffer: PBS with 0.5 % BSA and 0.09% Sodium Azide.
Reactivity	Bovine, Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified Bovine Lipoprotein Lipase
Specificity	This Monoclonal antibody is directed against the CII binding site. Blocks the catalytic activity of Bovine milk lipase. A small partial cross-reactivity with Human Heparin Plasma Lipase activity was observed (Ref. 1).
Formulation	PBS, pH 7.4 State: Purified State: Lyophilized purified IgG fraction Stabilizer: 0.5% BSA Preservative: 0.09% Sodium Azide
Reconstitution Method	Restore with 1 ml distilled water
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Gene Name	lipoprotein lipase
Database Link	Entrez Gene 4023 Human UniProt ID P06858
Background	Lipoprotein lipase (LPL) is the central enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. Evidence has been provided that LPL produced by macrophages in the vessel wall exerts proatherogenic effects. The atherogenic effects of LPL have been mainly attributed to its ability to favor lipid accumulation within macrophages present in the atherosclerotic lesion. Recently, it has also been shown that LPL promote the development of atherosclerosis through facilitation of monocyte adhesion to endothelial cells, stimulation of tumor necrosis factor alpha (TNF ) secretion and induction of vascular smooth muscle cell proliferation.
Synonyms	LPL, LIPD, EC=3.1.1.34
Reference Data

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