LRP1 Mouse Monoclonal Antibody [Clone ID: 5A6]

Specifications

Product Data
Clone Name	5A6
Applications	FC, IF, IHC, WB
Recommend Dilution	Immunoblotting. Flow Cytometry. Immunofluorescence. Immunohistochemistry (Dilute 1/20). Neutralizing effects of 5A6 have also been reported (cf. Basu et al., 2001).
Reactivity	Hamster, Human, Mouse, Rabbit, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human LRP/alpha2MR.
Specificity	This monoclonal antibody 5A6 specifically reacts with the 85 kD beta-chain of LRP/alpha2MR which is expressed in a restricted spectrum of cell types (for a recent review cf. Herz & Strickland). A strong immunohistochemical reaction is seen in hepatocytes, tissue macrophages, subsets of neurones and astrocytes in the central nervous system, fibroblasts, smooth muscle cells, and monocyte-derived foam cells in atherosclerotic lesions in the arterial wall. The antibody can also be used for the characterization of a subset of myelomonocytic subtypes of chronic and acute leukemia (CD 91). Cross-reacts with rabbit LDL receptor-related protein (LRP) or mouse LRP.
Formulation	Final solution contains 0.5% BSA in PBS buffer, pH 7.4 State: Purified State: Lyophilzed purified Ig fraction.
Reconstitution Method	Restore in 1 ml dist. water
Purification	Affinity Chromatography on Protein A.
Conjugation	Unconjugated
Storage Condition	For extended storage keep in aliquots at -20°C. Avoid repeated freezing and thawing.
Gene Name	LDL receptor related protein 1
Database Link	Entrez Gene 4035 Human UniProt ID Q07954
Synonyms	A2MR, APR, APOER
Reference Data

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