Cytokeratin 7 (KRT7) Mouse Monoclonal Antibody [Clone ID: RCK105]
CAT#: BM6003P
Cytokeratin 7 (KRT7) mouse monoclonal antibody, clone RCK105, Purified
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CNY 5,186.00
货期*
5周
规格
Specifications
Product Data | |
Clone Name | RCK105 |
Applications | FC, IF, IHC, WB |
Recommend Dilution | Immunoblotting. Flow Cytometry. Immunocytochemistry. Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Sections. Recommended Dilutions: 1/100-1/200 for Flow Cytometry, and for Immunohistochemistry with avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent, and 1/100-1/1000 for Immunoblotting . |
Reactivity | Canine, Feline, Goat, Hamster, Human, Mouse, Rat, Zebrafish |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Cytokeratins from the Human bladder carcinoma cell line T24. |
Specificity | RCK105 reacts exclusively with Cytokeratin 7 which is present in a subgroup of glandular epithelia and their tumors, as well as transitional epithelium and transitional carcinoma. |
Formulation | PBS with 0.09% Sodium Azide as preservative State: Purified State: Liquid purified IgG fraction |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freeze-thaw cycles. |
Gene Name | keratin 7 |
Database Link | |
Background | Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9-7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays. |
Synonyms | KRT7, KRT-7, SCL, CK-7, CK7, Keratin-7, K7, K-7, Sarcolectin |
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