LRPAP1 Rabbit Polyclonal Antibody
CAT#: BP5016
LRPAP1 rabbit polyclonal antibody, Serum
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CNY 4,280.00
货期*
5周
规格
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Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | Ligand blotting. Western blotting. Immunohistochemistry on Frozen Sections: 1/50-1/100 Immunohistochemistry on Paraffin Sections: 1/50-1/100 (microwave treatment recommended) |
Reactivity | Chicken, Human, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Recombinant Human RAP (Receptor-Associated Protein). |
Specificity | The antibody binds to an epitope of the C-terminal part of RAP, a sequence common to the Human VLDL receptor superfamily (glycoprotein 330 and LRP), the Chicken oocyte receptor for VLDL and Vitellogenin (LR8), and Glycoprotein 330/megalin from Rat. No reaction with LDL receptor. The antibody interferes with binding of VLDL and Vitellogenin Receptor. Binding is Ca2+-dependent with LR8. |
Formulation | State: Serum State: Liquid Stabilized antierum with 0.5% BSA and 0.09% Sodium Azide |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Gene Name | LDL receptor related protein associated protein 1 |
Database Link | |
Background | Low density lipoprotein receptor-related protein-associated protein 1 (RAP) interacts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330. It is present on the cell surface forming a complex with the alpha 2 macroglobulin receptor heavy and light chains. Binds LRP1B; binding is followed by internalization and degradation. In complex with the alpha 2 MR or gp330, it may have some role in the pathogenesis of membrane glomerular nephritis. |
Synonyms | Alpha-2-MRAP, RAP |
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