CCIN Guinea Pig Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Immunohistochemistry on frozen: 1/100; 1h at RT. Western blot: 1/2000 (ECL).
Reactivity	Bovine, Human
Host	Guinea Pig
Clonality	Polyclonal
Immunogen	Synthetic N-terminal domain (aa 1-24) of bovine calicin, coupled to KLH.
Specificity	Sperm head calyx protein calicin (mw 66,889; IEP 8.1; 588 amino acids), testis specific cytoskeletal protein Homologue to kelch protein of the ring canal structure of Drosophila ovaries. Useful to study spermiogenetic differentiation. Calicin is absent from pathologic forms like roundheaded or other post-acrosomal sheath defect sperm malformations.
Formulation	State: Serum State: Liquid serum contains 0.09% sodium azide
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C. DO NOT FREEZE!
Database Link	Entrez Gene 281041 Bovine UniProt ID Q28068
Background	Calicin is a basic protein of the sperm head cytoskeleton, necessary for normal morphology during sperm differentiation. This protein contains kelch repeats and a BTB/POZ domain and is intronless.
Synonyms	CCIN
Reference Data

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