Neurogenin3 (NEUROG3) Mouse Monoclonal Antibody [Clone ID: OTI3B5]

Specifications

Product Data
Clone Name	OTI3B5
Applications	IF, IHC, IP, WB
Recommend Dilution	WB 1:2000, IHC 1:50 - 1:150, IF 1:100
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full-length protein expressed in 293T cell transfected with human NEUROG3 expression vector
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	23.077 kDa
Gene Name	neurogenin 3
Database Link	NP_066279 Entrez Gene 50674 Human UniProt ID Q9Y4Z2
Background	Neurogenin-3 (NEUROG3) is expressed in endocrine progenitor cells and is required for endocrine cell development in the pancreas and intestine (Wang et al., 2006 [PubMed 16855267]). It belongs to a family of basic helix-loop-helix transcription factors involved in the determination of neural precursor cells in the neuroectoderm
Synonyms	Atoh5; bHLHa7; Math4B; NGN-3; ngn3
Reference Data
Protein Families	ES Cell Differentiation/IPS
Protein Pathways	Maturity onset diabetes of the young

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