alpha 1 Antitrypsin (SERPINA1) Mouse Monoclonal Antibody [Clone ID: OTI11G2]

Specifications

Product Data
Clone Name	OTI11G2
Applications	IHC, IP, WB
Recommend Dilution	WB 1:1000~2000, IHC 1:150, IP 2ug/500ul
Reactivity	Human, Dog, Monkey
Host	Mouse
Clonality	Monoclonal
Immunogen	Full-length protein expressed in 293T cell transfected with human SERPINA1 expression vector
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	46.7 kDa
Gene Name	serpin family A member 1
Database Link	NP_000286 Entrez Gene 480422 DogEntrez Gene 701361 MonkeyEntrez Gene 5265 Human UniProt ID P01009
Background	The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase,plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene.
Synonyms	A1A; A1AT; AAT; alpha1AT; PI; PI1; PRO2275
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways	Complement and coagulation cascades

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