PP5 (PPP5C) Mouse Monoclonal Antibody [Clone ID: OTI2G2]

Specifications

Product Data
Clone Name	OTI2G2
Applications	IF, IHC, WB
Recommend Dilution	WB 1:500~1000, IHC 1:50, IF 1:100
Reactivity	Human, Dog, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human PPP5C (NP_006238) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	56.7 kDa
Gene Name	protein phosphatase 5 catalytic subunit
Database Link	NP_006238 Entrez Gene 65179 RatEntrez Gene 612199 DogEntrez Gene 5536 Human UniProt ID P53041
Background	This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
Synonyms	PP5; PPP5; PPT
Reference Data
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	MAPK signaling pathway

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