FRA1 (FOSL1) Mouse Monoclonal Antibody [Clone ID: OTI12F9]

Specifications

Product Data
Clone Name	OTI12F9
Applications	IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:50
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full-length protein expressed in 293T cell transfected with human FOSL1 expression vector
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	29.4 kDa
Gene Name	FOS like 1, AP-1 transcription factor subunit
Database Link	NP_005429 Entrez Gene 14283 MouseEntrez Gene 25445 RatEntrez Gene 8061 Human UniProt ID P15407
Background	The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
Synonyms	FRA; fra-1; FRA1
Reference Data
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	Wnt signaling pathway

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