DAP Kinase 2 (DAPK2) Mouse Monoclonal Antibody [Clone ID: OTI1C8]

Specifications

Product Data
Clone Name	OTI1C8
Applications	FC, IHC, IP, WB
Recommend Dilution	WB 1:2000, IHC 1:50, FLOW 1:100, IP 2ug/500ul
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human DAPK2 (NP_055141) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	42.7 kDa
Gene Name	death associated protein kinase 2
Database Link	NP_055141 Entrez Gene 13143 MouseEntrez Gene 23604 Human UniProt ID Q9UIK4
Background	This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites. [provided by RefSeq]
Synonyms	DRP-1; DRP1
Reference Data
Protein Families	Druggable Genome, Protein Kinase
Protein Pathways	Bladder cancer, Pathways in cancer

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