Adenylosuccinate Lyase (ADSL) Mouse Monoclonal Antibody [Clone ID: OTI2D10]
CAT#: CF501810
Carrier-free (BSA/glycerol-free) ADSL mouse monoclonal antibody, clone OTI2D10 (formerly 2D10)
Formulation: Standard
View other "OTI2D10" antibodies (4)
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CNY 3,999.00
Specifications
Product Data | |
Clone Name | OTI2D10 |
Applications | FC, IHC, WB |
Recommend Dilution | WB 1:500~2000, IHC 1:150, FLOW 1:100 |
Reactivity | Human, Dog, Rat, Monkey, Mouse |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human ADSL (NP_000017) produced in HEK293T cell. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 54.7 kDa |
Gene Name | adenylosuccinate lyase |
Database Link | |
Background | Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Synonyms | AMPS; ASASE; ASL |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Alanine, aspartate and glutamate metabolism, Metabolic pathways, Purine metabolism |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA501810 | ADSL (Adenylosuccinate Lyase) mouse monoclonal antibody, clone OTI2D10 (formerly 2D10) |
CNY 1,999.00 |
|
TA501810AM | ADSL (Adenylosuccinate Lyase) mouse monoclonal antibody, clone OTI2D10 (formerly 2D10), Biotinylated |
CNY 3,990.00 |
|
TA501810BM | ADSL (Adenylosuccinate Lyase) mouse monoclonal antibody, clone OTI2D10 (formerly 2D10), HRP conjugated |
CNY 3,990.00 |
|
TA501810S | ADSL (Adenylosuccinate Lyase) mouse monoclonal antibody, clone OTI2D10 (formerly 2D10) |
CNY 800.00 |
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