S6K1 (RPS6KB1) Mouse Monoclonal Antibody [Clone ID: OTI4G4]
CAT#: CF502930
Carrier-free (BSA/glycerol-free) RPS6KB1 mouse monoclonal antibody, clone OTI4G4 (formerly 4G4)
Formulation: Standard
View other "OTI4G4" antibodies (4)
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CNY 3,999.00
Specifications
Product Data | |
Clone Name | OTI4G4 |
Applications | FC, IF, WB |
Recommend Dilution | WB 1:2000, IF 1:100, FLOW 1:100 |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human RPS6KB1 (NP_003152) produced in HEK293T cell. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 59 kDa |
Gene Name | ribosomal protein S6 kinase B1 |
Database Link | |
Background | This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized. [provided by RefSeq] |
Synonyms | p70 S6KA; p70(S6K)-alpha; p70-alpha; p70-S6K; PS6K; S6K; S6K-beta-1; S6K1; STK14A |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | Acute myeloid leukemia, ErbB signaling pathway, Fc gamma R-mediated phagocytosis, Insulin signaling pathway, mTOR signaling pathway, TGF-beta signaling pathway |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA502930 | RPS6KB1 (S6K) mouse monoclonal antibody, clone OTI4G4 (formerly 4G4) |
CNY 1,999.00 |
|
TA502930AM | RPS6KB1 (S6K) mouse monoclonal antibody, clone OTI4G4 (formerly 4G4), Biotinylated |
CNY 3,990.00 |
|
TA502930BM | RPS6KB1 (S6K) mouse monoclonal antibody, clone OTI4G4 (formerly 4G4), HRP conjugated |
CNY 3,990.00 |
|
TA502930S | RPS6KB1 (S6K) mouse monoclonal antibody, clone OTI4G4 (formerly 4G4) |
CNY 800.00 |