PDXK Mouse Monoclonal Antibody [Clone ID: OTI3G2]

Specifications

Product Data
Clone Name	OTI3G2
Applications	FC, IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150, FLOW 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human PDXK (NP_003672) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	34.9 kDa
Gene Name	pyridoxal kinase
Database Link	NP_003672 Entrez Gene 83578 RatEntrez Gene 216134 MouseEntrez Gene 8566 Human UniProt ID O00764
Background	The protein encoded by this gene phosphorylates vitamin B6, a step required for the conversion of vitamin B6 to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. The encoded protein is cytoplasmic and probably acts as a homodimer. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq]
Synonyms	C21orf97; C21orf124; HEL-S-1a; PKH; PNK; PRED79
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Metabolic pathways, Vitamin B6 metabolism

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