GPR48 (LGR4) Mouse Monoclonal Antibody [Clone ID: OTI5B8]

Specifications

Product Data
Clone Name	OTI5B8
Applications	FC, WB
Recommend Dilution	WB 1:500, FLOW 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 230-540 of human LGR4 (NP_060960 ) produced in HEK293T Cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	leucine rich repeat containing G protein-coupled receptor 4
Database Link	NP_060960 Entrez Gene 107515 MouseEntrez Gene 286994 RatEntrez Gene 55366 Human UniProt ID Q9BXB1
Background	G protein-coupled receptors (GPCRs) play key roles in a variety of physiologic functions. Members of the leucine-rich GPCR (LGR) family, such as GPR48, have multiple N-terminal leucine-rich repeats (LRRs) and a 7-transmembrane domain (Weng et al., 2008 [PubMed 18424556]). [supplied by OMIM]
Synonyms	BNMD17; GPR48
Reference Data
Protein Families	Druggable Genome, GPCR, Transmembrane

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