Cytochrome P450 17A1 (CYP17A1) Mouse Monoclonal Antibody [Clone ID: OTI9H4]
CAT#: CF503395
Carrier-free (BSA/glycerol-free) CYP17A1 mouse monoclonal antibody, clone OTI9H4 (formerly 9H4)
Formulation: Standard
View other "OTI9H4" antibodies (5)
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CNY 3,999.00
Cited in 1 publication. |
Specifications
Product Data | |
Clone Name | OTI9H4 |
Applications | WB |
Recommend Dilution | WB 1:500 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human CYP17A1(NP_000093) produced in HEK293T cell. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 57.2 kDa |
Gene Name | cytochrome P450 family 17 subfamily A member 1 |
Database Link | |
Background | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq] |
Synonyms | CPT7; CYP17; P450C17; S17AH |
Reference Data | |
Protein Families | Druggable Genome, P450 |
Protein Pathways | C21-Steroid hormone metabolism, Metabolic pathways |
Citations (1)
The use of this Antibodies has been cited in the following citations: |
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Functional characterization of the G162R and D216H genetic variants of human CYP17A1
,null,
The Journal of steroid biochemistry and molecular biology
,PubMed ID 29229304
[CYP17A1]
|
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA503395 | CYP17A1 mouse monoclonal antibody, clone OTI9H4 (formerly 9H4) |
CNY 1,999.00 |
|
TA503395AM | CYP17A1 mouse monoclonal antibody, clone OTI9H4 (formerly 9H4), Biotinylated |
CNY 3,990.00 |
|
TA503395BM | CYP17A1 mouse monoclonal antibody, clone OTI9H4 (formerly 9H4), HRP conjugated |
CNY 3,990.00 |
|
TA503395S | CYP17A1 mouse monoclonal antibody, clone OTI9H4 (formerly 9H4) |
CNY 800.00 |
|
TA600327 | CYP17A1 mouse monoclonal capture antibody, validated for Luminex assays |
CNY 3,600.00 |
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