FDFT1 Mouse Monoclonal Antibody [Clone ID: OTI2F10]

Specifications

Product Data
Clone Name	OTI2F10
Applications	IF, IHC, WB
Recommend Dilution	WB 1:200~500, IHC 1:150, IF 1:100
Reactivity	Human, Monkey, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human FDFT1(NP_004453) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	47.9 kDa
Gene Name	farnesyl-diphosphate farnesyltransferase 1
Database Link	NP_004453 Entrez Gene 14137 MouseEntrez Gene 29580 RatEntrez Gene 696396 MonkeyEntrez Gene 2222 Human UniProt ID P37268
Background	This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq]
Synonyms	DGPT; ERG9; SQS; SS
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Metabolic pathways, Steroid biosynthesis

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