ARH (LDLRAP1) Mouse Monoclonal Antibody [Clone ID: OTI2B2]

Specifications

Product Data
Clone Name	OTI2B2
Applications	FC, IF, WB
Recommend Dilution	WB 1:2000, IF 1:100, FLOW 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human LDLRAP1(NP_056442) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	33.7 kDa
Gene Name	low density lipoprotein receptor adaptor protein 1
Database Link	NP_056442 Entrez Gene 100017 MouseEntrez Gene 500564 RatEntrez Gene 26119 Human UniProt ID Q5SW96
Background	The protein encoded by this gene is a cytosolic protein which contains a phosphotyrosine binding (PTD) domain. The PTD domain has been found to interact with the cytoplasmic tail of the LDL receptor. Mutations in this gene lead to LDL receptor malfunction and cause the disorder autosomal recessive hypercholesterolaemia. [provided by RefSeq]
Synonyms	ARH; ARH1; ARH2; FHCB1; FHCB2
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Endocytosis

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