C1S Mouse Monoclonal Antibody [Clone ID: OTI2A8]

Specifications

Product Data
Clone Name	OTI2A8
Applications	IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150
Reactivity	Human, Rat, Monkey, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human C1S(NP_001725) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	74.8 kDa
Gene Name	complement C1s
Database Link	NP_001725 Entrez Gene 192262 RatEntrez Gene 714589 MonkeyEntrez Gene 716 Human UniProt ID P09871
Background	This gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency. [provided by RefSeq, Mar 2009]
Synonyms	FLJ44757
Reference Data
Protein Families	Druggable Genome, Protease
Protein Pathways	Complement and coagulation cascades, Systemic lupus erythematosus

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