Cytochrome P450 2B6 (CYP2B6) Mouse Monoclonal Antibody [Clone ID: OTI3D5]
CAT#: CF504328
Carrier-free (BSA/glycerol-free) CYP2B6 mouse monoclonal antibody, clone OTI3D5 (formerly 3D5)
Formulation: Standard
View other "OTI3D5" antibodies (4)
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CNY 3,999.00
Cited in 2 publications. |
Specifications
Product Data | |
Clone Name | OTI3D5 |
Applications | FC, IF, IHC, WB |
Recommend Dilution | WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100 |
Reactivity | Human, Dog, Rat, Monkey, Mouse |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human CYP2B6(NP_000758) produced in HEK293T cell. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 56.1 kDa |
Gene Name | cytochrome P450 family 2 subfamily B member 6 |
Database Link | |
Background | This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008] |
Synonyms | CPB6; CYP2B; CYP2B7; CYP2B7P; CYPIIB6; EFVM; IIB1; P450 |
Reference Data | |
Protein Families | Druggable Genome, P450 |
Protein Pathways | Arachidonic acid metabolism, Drug metabolism - cytochrome P450, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Retinol metabolism |
Citations (2)
The use of this Antibodies has been cited in the following citations: |
---|
Identification of rhythmic human CYPs and their circadian regulators using synchronized hepatoma cells.
,null,
Xenobiotica; the fate of foreign compounds in biological systems
,PubMed ID 32118505
[CYP2B6]
|
Hepatic Expression of Detoxification Enzymes Is Decreased in Human Obstructive Cholestasis Due to Gallstone Biliary Obstruction
,null,
PLoS ONE
,PubMed ID 25798860
[CYP2B6]
|
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA504328 | CYP2B6 (Cytochrome P450 2B6) mouse monoclonal antibody, clone OTI3D5 (formerly 3D5) |
CNY 1,999.00 |
|
TA504328AM | CYP2B6 (Cytochrome P450 2B6) mouse monoclonal antibody, clone OTI3D5 (formerly 3D5), Biotinylated |
CNY 3,990.00 |
|
TA504328BM | CYP2B6 (Cytochrome P450 2B6) mouse monoclonal antibody, clone OTI3D5 (formerly 3D5), HRP conjugated |
CNY 3,990.00 |
|
TA504328S | CYP2B6 (Cytochrome P450 2B6) mouse monoclonal antibody, clone OTI3D5 (formerly 3D5) |
CNY 800.00 |
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