Cystatin C (CST3) Mouse Monoclonal Antibody [Clone ID: OTI2C11]
CAT#: CF504493
Carrier-free (BSA/glycerol-free) CST3 mouse monoclonal antibody, clone OTI2C11 (formerly 2C11)
Formulation: Standard
View other "OTI2C11" antibodies (6)
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CNY 3,999.00
Specifications
Product Data | |
Clone Name | OTI2C11 |
Applications | WB |
Recommend Dilution | WB 1:2000 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human CST3(NP_000090) produced in HEK293T cell. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 13.3 kDa |
Gene Name | cystatin C |
Database Link | |
Background | The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. [provided by RefSeq] |
Synonyms | ARMD11; HEL-S-2 |
Reference Data | |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA504493 | CST3 (Cystatin C) mouse monoclonal antibody, clone OTI2C11 (formerly 2C11) |
CNY 1,999.00 |
|
TA504493AM | CST3 (Cystatin C) mouse monoclonal antibody, clone OTI2C11 (formerly 2C11), Biotinylated |
CNY 3,990.00 |
|
TA504493BM | CST3 (Cystatin C) mouse monoclonal antibody, clone OTI2C11 (formerly 2C11), HRP conjugated |
CNY 3,990.00 |
|
TA504493S | CST3 (Cystatin C) mouse monoclonal antibody, clone OTI2C11 (formerly 2C11) |
CNY 800.00 |
|
TA600252 | CST3 mouse monoclonal capture antibody, validated for Luminex assays |
CNY 2,600.00 |
|
TA700252 | CST3 biotinylated mouse monoclonal detection antibody, validated for Luminex assays |
CNY 2,700.00 |
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