Transferrin Receptor 2 (TFR2) Mouse Monoclonal Antibody [Clone ID: OTI2B4]

Specifications

Product Data
Clone Name	OTI2B4
Applications	FC, IF, WB
Recommend Dilution	WB 1:500~2000, IF 1:100, FLOW 1:100
Reactivity	Human, Rat, Monkey, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human TFR2(NP_003218) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	88.6 kDa
Gene Name	transferrin receptor 2
Database Link	NP_003218 Entrez Gene 50765 MouseEntrez Gene 288562 RatEntrez Gene 719240 MonkeyEntrez Gene 7036 Human UniProt ID Q9UP52
Background	This gene encodes a single-pass type II membrane protein, which is a member of the transferrin receptor-like family. This protein mediates cellular uptake of transferrin-bound iron, and may be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. Mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
Synonyms	HFE3; TFRC2
Reference Data
Protein Families	Druggable Genome, Protease, Transmembrane

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