SIVA (SIVA1) Mouse Monoclonal Antibody [Clone ID: OTI2F8]

Specifications

Product Data
Clone Name	OTI2F8
Applications	IF, IHC, WB
Recommend Dilution	WB 1:1000, IF: 1:100
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human SIVA1(NP_006418) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	18.5 kDa
Gene Name	SIVA1 apoptosis inducing factor
Database Link	NP_006418 Entrez Gene 10572 Human UniProt ID O15304
Background	This gene encodes a protein with an important role in the apoptotic (programmed cell death) pathway induced by the CD27 antigen, a member of the tumor necrosis factor receptor (TFNR) superfamily. The CD27 antigen cytoplasmic tail binds to the N-terminus of this protein. Two alternatively spliced transcript variants encoding distinct proteins have been described. [provided by RefSeq, Jul 2008]
Synonyms	CD27BP; SIVA; Siva-1; Siva-2
Reference Data
Protein Families	Druggable Genome

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