SPHK1 Mouse Monoclonal Antibody [Clone ID: OTI1A6]
CAT#: CF507215
Carrier-free (BSA/glycerol-free) SPHK1 mouse monoclonal antibody, clone OTI1A6 (formerly 1A6)
Formulation: Standard
View other "OTI1A6" antibodies (4)
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CNY 3,999.00
Specifications
Product Data | |
Clone Name | OTI1A6 |
Applications | IF, IHC, WB |
Recommend Dilution | WB 1:400~4000, IHC 1:150, IF 1:100 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human SPHK1(NP_068807) produced in HEK293T cell. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 43.8 kDa |
Gene Name | sphingosine kinase 1 |
Database Link | |
Background | The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] |
Synonyms | SPHK |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Calcium signaling pathway, Fc gamma R-mediated phagocytosis, Metabolic pathways, Sphingolipid metabolism, VEGF signaling pathway |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA507215 | SPHK1 mouse monoclonal antibody, clone OTI1A6 (formerly 1A6) |
CNY 1,999.00 |
|
TA507215AM | SPHK1 mouse monoclonal antibody, clone OTI1A6 (formerly 1A6), Biotinylated |
CNY 3,990.00 |
|
TA507215BM | SPHK1 mouse monoclonal antibody, clone OTI1A6 (formerly 1A6), HRP conjugated |
CNY 3,990.00 |
|
TA507215S | SPHK1 mouse monoclonal antibody, clone OTI1A6 (formerly 1A6) |
CNY 800.00 |