TMS1 (PYCARD) Mouse Monoclonal Antibody [Clone ID: OTI3E9]
CAT#: CF800081
Carrier-free (BSA/glycerol-free) PYCARD mouse monoclonal antibody, clone OTI3E9 (formerly 3E9)
Formulation: Standard
View other "OTI3E9" antibodies (4)
Need it in bulk or conjugated?
Get a free quote
CNY 3,999.00
Specifications
Product Data | |
Clone Name | OTI3E9 |
Applications | FC, IHC, WB |
Recommend Dilution | WB 1:500~2000, IHC 1:150, FLOW 1:100 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human PYCARD (NP_037390) produced in E.coli. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 21.4 kDa |
Gene Name | PYD and CARD domain containing |
Database Link | |
Background | This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Synonyms | ASC; CARD5; TMS; TMS-1; TMS1 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Cytosolic DNA-sensing pathway, NOD-like receptor signaling pathway |
Documents
Product Manuals |
FAQs |
SDS |
Resources
抗体相关资料 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA800081 | PYCARD (TMS1) mouse monoclonal antibody, clone OTI3E9 (formerly 3E9) |
CNY 1,999.00 |
|
TA800081AM | PYCARD mouse monoclonal antibody,clone 3E9, Biotinylated |
CNY 3,990.00 |
|
TA800081BM | PYCARD mouse monoclonal antibody,clone 3E9, HRP conjugated |
CNY 3,990.00 |
|
TA800081S | PYCARD (TMS1) mouse monoclonal antibody, clone OTI3E9 (formerly 3E9) |
CNY 800.00 |