CK1 epsilon (CSNK1E) Mouse Monoclonal Antibody [Clone ID: OTI2B3]

Specifications

Product Data
Clone Name	OTI2B3
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 153-416 of human CSNK1E (NP_689407) produced in E.coli.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	casein kinase 1 epsilon
Database Link	NP_689407 Entrez Gene 27373 MouseEntrez Gene 58822 RatEntrez Gene 1454 Human UniProt ID P49674
Background	The protein encoded by this gene is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms	CKIepsilon; HCKIE
Reference Data
Protein Families	Druggable Genome, Protein Kinase
Protein Pathways	Circadian rhythm - mammal, Hedgehog signaling pathway, Wnt signaling pathway

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