NR0B2 Mouse Monoclonal Antibody [Clone ID: OTI7B5]
CAT#: CF806321
Carrier-free (BSA/glycerol-free) NR0B2 mouse monoclonal antibody, clone OTI7B5 (formerly 7B5)
Formulation: Standard
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CNY 3,999.00
Specifications
Product Data | |
Clone Name | OTI7B5 |
Applications | IHC, WB |
Recommend Dilution | WB 1:2000 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human NR0B2 (NP_068804) produced in E.coli. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | nuclear receptor subfamily 0 group B member 2 |
Database Link | |
Background | The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. [provided by RefSeq, Jul 2008] |
Synonyms | SHP; SHP1 |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA806321 | NR0B2 mouse monoclonal antibody, clone OTI7B5 (formerly 7B5) |
CNY 1,999.00 |
|
TA806321AM | NR0B2 mouse monoclonal antibody, clone OTI7B5 (formerly 7B5), Biotinylated |
CNY 3,990.00 |
|
TA806321BM | NR0B2 mouse monoclonal antibody, clone OTI7B5 (formerly 7B5), HRP conjugated |
CNY 3,990.00 |
|
TA806321S | NR0B2 mouse monoclonal antibody, clone OTI7B5 (formerly 7B5) |
CNY 800.00 |