SIRT1 Mouse Monoclonal Antibody [Clone ID: OTI12H3]

CAT#: CF809859

Carrier-free (BSA/glycerol-free) SIRT1 mouse monoclonal antibody, clone OTI12H3

Formulation: Standard Carrier-Free



  View other "OTI12H3" antibodies (4)

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CNY 3,999.00


货期*
2周

规格
    • 100 ug

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Specifications

Product Data
Clone Name OTI12H3
Applications WB
Recommend Dilution WB 1:2000
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 552-676 of human SIRT1(NP_036370) produced in E.coli.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 81.5 kDa
Gene Name sirtuin 1
Background This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
Synonyms SIR2; SIR2alpha; SIR2L1
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency, Transcription Factors
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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