PRMT7 Mouse Monoclonal Antibody [Clone ID: OTI10A8]

Specifications

Product Data
Clone Name	OTI10A8
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human PRMT7 (NP_061896) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	78.3 kDa
Gene Name	protein arginine methyltransferase 7
Database Link	NP_061896 Entrez Gene 214572 MouseEntrez Gene 54496 Human UniProt ID Q9NVM4
Background	Arginine methylation is an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, using S-adenosylmethionine (AdoMet) as the methyl donor. Arginine methylation is implicated in signal transduction, RNA transport, and RNA splicing (Miranda et al., 2004 [PubMed 15044439]). [supplied by OMIM, Mar 2008]. Transcript Variant: This variant (2) lacks an exon in the 5' UTR and in the 5' coding region compared to variant 1. The resulting protein (isoform 2) is shorter but has the same N- and C-termini compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK304605.1 [ECO:0000332] RNAseq introns :: single sample supports all introns ERS025087, ERS025093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.
Synonyms	FLJ10640; KIAA1933
Reference Data
Protein Families	Druggable Genome

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