SHARP2 (BHLHE40) Mouse Monoclonal Antibody [Clone ID: OTI6D6]

Specifications

Product Data
Clone Name	OTI6D6
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 1-313 of human BHLHE40 (NP_003661) produced in E.coli.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	45.3 kDa
Gene Name	basic helix-loop-helix family member e40
Database Link	NP_003661 Entrez Gene 20893 MouseEntrez Gene 79431 RatEntrez Gene 8553 Human UniProt ID O14503
Background	This gene encodes a basic helix-loop-helix protein expressed in various tissues. The encoded protein can interact with ARNTL or compete for E-box binding sites in the promoter of PER1 and repress CLOCK/ARNTL's transactivation of PER1. This gene is believed to be involved in the control of circadian rhythm and cell differentiation. [provided by RefSeq, Feb 2014]
Synonyms	BHLHB2; DEC1; HLHB2; SHARP-2; STRA13; Stra14
Reference Data
Protein Families	Transcription Factors
Protein Pathways	Circadian rhythm - mammal

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