MLH1 Mouse Monoclonal Antibody [Clone ID: OTI3C1]
CAT#: CF810261
Carrier-free (BSA/glycerol-free) MLH1 mouse monoclonal antibody,clone OTI3C1
Formulation: Standard
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CNY 3,999.00
Specifications
Product Data | |
Clone Name | OTI3C1 |
Applications | IHC, WB |
Recommend Dilution | WB 1:500~2000, IHC 1:1000 |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 299-527 of human MLH1(NP_000240) produced in E.coli. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 84.4 kDa |
Gene Name | mutL homolog 1 |
Database Link | |
Background | This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined. [provided by RefSeq, Nov 2009] |
Synonyms | COCA2; FCC2; hMLH1; HNPCC; HNPCC2; MMRCS1 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Colorectal cancer, Endometrial cancer, Mismatch repair, Pathways in cancer |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA810261 | MLH1 mouse monoclonal antibody,clone OTI3C1 |
CNY 1,999.00 |
|
TA810261AM | MLH1 mouse monoclonal antibody,clone OTI3C1, Biotinylated |
CNY 3,990.00 |
|
TA810261BM | MLH1 mouse monoclonal antibody,clone OTI3C1, HRP conjugated |
CNY 3,990.00 |
|
TA810261S | MLH1 mouse monoclonal antibody,clone OTI3C1 |
CNY 800.00 |