MRC2 Mouse Monoclonal Antibody [Clone ID: OTI9G4]

Specifications

Product Data
Clone Name	OTI9G4
Applications	IHC, WB
Recommend Dilution	WB 1:500~2000, IHC 1:5000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human MRC2 (NP_006030) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	166.5 kDa
Gene Name	mannose receptor C type 2
Database Link	NP_006030 Entrez Gene 17534 MouseEntrez Gene 498011 RatEntrez Gene 9902 Human UniProt ID Q9UBG0
Background	This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease. [provided by RefSeq, Feb 2012]
Synonyms	CD280; CLEC13E; ENDO180; UPARAP
Reference Data
Protein Families	Druggable Genome, Transmembrane

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