BCMA (TNFRSF17) Mouse Monoclonal Antibody [Clone ID: OTI3H5]

Specifications

Product Data
Clone Name	OTI3H5
Applications	FC
Recommend Dilution	FC 1:100
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant full length protein of human TNFRSF17/BCMA (NP_001183) produced in HEK293 cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	20.1 kDa
Gene Name	TNF receptor superfamily member 17
Database Link	NP_001183 Entrez Gene 608 Human UniProt ID Q02223
Background	The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008]
Synonyms	BCM; BCMA; CD269; TNFRSF13A
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Cytokine-cytokine receptor interaction

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