PAH Mouse Monoclonal Antibody [Clone ID: OTI4F6]

Specifications

Product Data
Clone Name	OTI4F6
Applications	WB
Recommend Dilution	WB 1:500
Reactivity	Human,Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human PAH (NP_000268) produced in E.coli.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws.
Predicted Protein Size	51.8 kDa
Gene Name	phenylalanine hydroxylase
Database Link	NP_000268 Entrez Gene 18478 MouseEntrez Gene 5053 Human UniProt ID P00439
Background	This gene encodes a member of the biopterin-dependent aromatic amino acid hydroxylase protein family. The encoded phenylalanine hydroxylase enzyme hydroxylates phenylalanine to tyrosine and is the rate-limiting step in phenylalanine catabolism. Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria. [provided by RefSeq, Aug 2017]
Synonyms	PH; PKU; PKU1
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Metabolic pathways, Phenylalanine, tyrosine and tryptophan biosynthesis, Phenylalanine metabolism

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