Cd8b1 Mouse Monoclonal Antibody [Clone ID: F9(1)]

Specifications

Product Data
Clone Name	F9(1)
Applications	CT
Recommend Dilution	Flow Cytometry.
Reactivity	Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Recipient: ((B6xB6-Ly-2a)F1xB6-Ly-2a)) offspring (Ly-2a homozygous). Donor: B6-Ly-2a3a,H-2k. Fusion Partner: Spleen from immunized recipient fused with myeloma P3/X63-Ag8.
Specificity	This Monoclonal antibody reacts with a sub-population of T-lymphocytes expressing the Ly-3.1 phenotype, but does not react with lymphocytes from mouse strains expressing the Ly-3.2 phenotype.
Formulation	State: Supernatant State: Lyophilized Supernatant
Reconstitution Method	Restore with 1.0 ml of distilled water
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	CD8 antigen, beta chain 1
Database Link	Entrez Gene 12526 Mouse UniProt ID P10300
Background	The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
Synonyms	CD8B, CD8B1
Note	This reagent is not sold sterile, but can be sterilized by filtration if necessary. To minimize loss of volume during filtration, dilute to the final working concentration in the appropriate medium before filtration.
Reference Data

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