Basophils Mouse Monoclonal Antibody [Clone ID: 212H6.16]

Specifications

Product Data
Clone Name	212H6.16
Applications	IF
Recommend Dilution	IF
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	enriched-human tonsillar pDCs
Specificity	human basophils and mast cells. no-cross reactivity on mouse basophil
Formulation	PBS 50% glycerol Label: Alexa Fluor 546
Concentration	lot specific
Purification	QMA Hyper D Ion exchange chromatography
Conjugation	Alexa Fluor 546
Storage Condition	-20°C. KEEP CONTENTS STERILE: no preservative. Coupled antibodies: glycerol protects from freezing.
Background	Basophils and mast cells are multifunctional hematopoietic effector cells involved in allergic and inflammatory reactions. Immediate allergy is caused by release of chemical mediators by these cell types. In human peripheral blood, 212H6.16 is an antibody specific to a yet non-identified cell-surface structure present on basophils. 212H6.16 does not induce basophil degranulation, and is therefore a valuable tool for the isolation and study of human basophils. Tonsillar epithelium and skin keratinocytes are also stained by 212H6 in situ: antigen expression in tonsil is restricted to cells lining the epithelial crypts. (Bendriss-Vermare N.et al, Leukocyte Typing VII, White Cell Differentiation Antigen MC13, part 9, myeloid cells, 425-30, 2001; Editor Mason).
Synonyms	Basophil cells
Reference Data

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