CD1 (CD1A) Mouse Monoclonal Antibody [Clone ID: 214A9.01]

Specifications

Product Data
Clone Name	214A9.01
Applications	FC, IF
Recommend Dilution	IF
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	in vitro derived human DCs (GMCSF + TNFα)
Specificity	human CD1a (epitope in extracellular domain).
Formulation	100 μg in 200 μl / 50 μg in 100 μl PBS 50% glycerol Label: Alexa Fluor 546
Concentration	lot specific
Purification	QMA Hyper D ion exchange chromatography
Conjugation	Alexa Fluor 546
Storage Condition	-20°C. KEEP CONTENTS STERILE: no preservative. Coupled antibodies: glycerol protects from freezing.
Gene Name	CD1a molecule
Database Link	Entrez Gene 909 Human UniProt ID P06126
Background	CD1 family molecules have a homologous structure to MHC class I. They are monomorphic proteins of 50 kDa non-covalently associated with β2-microglobulin. Human CD1a molecules are divided in 2 groups. Group 1 includes CD1a, CD1b, and CD1c, while group 2 consists of the CD1d molecule. CD1a is mainly expressed at the cell-surface and in recycling vesicles. CD1a occurs in Birbeck’s granules of Langerhans cells and plays a role in presentation of non-peptide antigens. CD1a is expressed in vitro on CD34+ generated DCs and on monocyte-derived DCs. <br /><em>(Burdin N. et al, 1999 ; Curr. Opin. Immunol., 11:326-31 ; Valladeau J. et al, 1999; Immunity, 12:71-81)</em>
Synonyms	T6/Leu-6, hTa1
Reference Data

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