CD21 (CR2) (CD21L) Mouse Monoclonal Antibody [Clone ID: 7D6]

Specifications

Product Data
Clone Name	7D6
Applications	IHC
Recommend Dilution	IHC frozen section. Usage recommendation: *This monoclonal antibody may be used between 1-15 μg/ml.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	enriched-human tonsillar FDCs (follicular dendritic cells)
Specificity	human follicular dendritic cells
Formulation	State: Purified State: 100 μg in 200 μl / 50 μg in 100 μl Tris-NaCl pH 8
Concentration	lot specific
Purification	QMA Hyper D ion exchange chromatography
Conjugation	Unconjugated
Storage Condition	-20°C. KEEP CONTENTS STERILE: no preservative. Purified antibodies: avoid repeated freeze/thaw cycles.
Gene Name	complement component 3d receptor 2
Database Link	Entrez Gene 1380 Human UniProt ID P20023
Background	An antibody has been generated that specifically recognizes human follicular dendritic cells (FDCs) on the long CR2 / CD21L isoform (CD21L). Follicular dendritic cells represent a cell-type ontogenetically distinct from all other Dendritic Cells (DCs). They are found within B lymphocyte follicles of secondary lymphoid tissue. At the opposite, B lymphocytes selectively express the short CR2 / CD21 lacking exon 10a (CD21S). mAb 7D6 does not recognize CD21 expressed on other cells. (Liu Y.J. et al, 1997; J. Exp. Med.185: 165-170)
Synonyms	Complement receptor type 2, CR2, C3DR, C3d receptor, EBV Receptor, Dendritic Cell Marker
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.