LAMP3 Mouse Monoclonal Antibody [Clone ID: 104G4]

CAT#: DDX0190A647-100

LAMP3 mouse monoclonal antibody, clone 104G4



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CNY 6,000.00


货期*
4周

规格
    • 100 ug

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Specifications

Product Data
Clone Name 104G4
Applications FC
Recommend Dilution Intracyto Flow cytometry
Reactivity Human, Sheep
Host Mouse
Clonality Monoclonal
Immunogen human DC-LAMP alkaline phosphatase fusion protein
Specificity human DC-LAMP (epitope in intracytoplasmic domain). 
Species cross-reactivity: sheep.
Formulation PBS 50% glycerol
Label: Alexa Fluor 647
Concentration lot specific
Conjugation Alexa Fluor 647
Storage Condition -20°C. KEEP CONTENTS STERILE: no preservative.
Coupled antibodies: glycerol protects from freezing.
Gene Name lysosomal associated membrane protein 3
Background The dendritic cell lysosomal-associated membrane protein (DC-LAMP)/CD208 is a type I integral transmembrane glycoprotein mostly homologous to CD68, of about 45 kDa in mouse and 90 kDa in human (glycosylation), with a bipartite C-terminal structure divided by a serine/proline rich region, a transmembrane domain and a conserved tyrosine-based lysosomal targeting motif in its cytoplasmic tail. Initially cloned as a specific marker of human mature dendritic cells (DCs), DC-LAMP has been subsequently shown to be expressed in alveolar type II pneumocytes. In both cell types, the molecule is found in the limiting membrane of intracellular multi-lamellar bodies, known as MIIC (MHC class II compartments) in human mature DCs and as lung surfactant-containing lamellar bodies in type II pneumocytes. In the latter cell type, DC-LAMP expression is also detected at the cell surface.
(de Saint-Vis B et al, 1998 ; Immunity ; 9:325-336)
Synonyms DCLAMP, DC-LAMP, TSC403, Dendritic Cell Marker
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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