SEMA6A Mouse Monoclonal Antibody [Clone ID: 118E7]

CAT#: DDX0463P-100

SEMA6A mouse monoclonal antibody, clone 118E7



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CNY 4,988.00


货期*
4周

规格
    • 100 ug

Product images

Specifications

Product Data
Clone Name 118E7
Applications FC
Recommend Dilution DDX0463P-50 / DDX0463P-100 Purified: Surface Flow Cytometry.
DDX0463A488-50 / DDX0463A488-100 Alexa-fluor®488: Surface Flow Cytometry. 
DDX0463A546-50 / DDX0463A546-100 Alexa-fluor®546: IF.
DDX0463A647-50 / DDX0463A647-100 Alexa- fluor®647: (on request) IHC, Flow cytometry. 

Usage recommendation:
*This monoclonal antibody may be used between 5-20 μg/ml.
*Optimal dilution should be determined by each laboratory for each application.
*Coupled antibody: to maintain RT before using.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen human recombinant SEMA-6A
Specificity Human SEMA-6A (epitope in extracellular domain).
Formulation Purified: 100 μg in 200μl / 50 μg in 100 μl Tris-NaCl pH 8.
Coupled: 100 μg in 200μl / 50 μg in 100 μl PBS 50% glycerol.
State: Purified
Concentration lot specific
Purification QMA Hyper D ion exchange chromatography
Conjugation Unconjugated
Storage Condition -20°C. KEEP CONTENTS STERILE: no preservative.
Purified antibodies: avoid repeated freeze/thaw cycles.
Coupled antibodies: glycerol protects from freezing.
Gene Name semaphorin 6A
Background Semaphorins represent a large family composed of 19 secreted, GPI-linked or transmembrane members divided into 5 classes (3 to 7) and characterized by the presence of a 500 amino acid Sema domain in the Nterminus. Initially described for their role in axon guidance and apoptosis during neuronal development, some semaphorins like the class 4 regulate immune functions and are involved in organogenesis and angiogenesis. The transmembrane class 6 semaphorins include 4 members (SEMA-6A to 6D). SEMA-6A features an intracellular binding site for regulatory Evl protein. In the immune system, SEMA6A protein is restricted in vitro and in vivo to an activation status of Langerhans cells. (Gautier G et al., 2006 Am J Pathol., 168: 453-65).
Synonyms Semaphorin-6A, Semaphorin VIA, Sema VIA, Semaphorin-6A-1, SEMA6A-1, SEMAQ, KIAA1368
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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