CD49b (ITGA2) Human Monoclonal Antibody [Clone ID: F2H11]

CAT#: DDX9021A488-100

CD49b (ITGA2) human monoclonal antibody, clone F2H11



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CNY 10,950.00


货期*
4周

规格
    • 100 ug

Product images

Specifications

Product Data
Clone Name F2H11
Applications FC, IF
Recommend Dilution Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F) .

Usage recommendation:

*This monoclonal antibody may be used between 5-25μg/ml.
*Optimal dilution should be determined by each laboratory for each application.
*Coupled antibody: to maintain RT before use.
Reactivity Human
Host Human
Clonality Monoclonal
Immunogen
CD40 activated and EBV immortalized human B lymphocytes
Specificity HPA5b (does not bind to HPA5a differing by a single amino acid).
Formulation
PBS, 50% glycerol

Label: Alexa Fluor 488
Concentration lot specific
Purification QMA Hyper D ion exchange chromatography
Conjugation Alexa Fluor 488
Storage Condition -20°C. KEEP CONTENTS STERILE: no preservative.
Purified antibodies: avoid repeated freeze/thaw cycles.
Coupled antibodies: glycerol protects from freezing.
Gene Name integrin subunit alpha 2
Background Neonatal AlloImmune Thrombocytopenia (NAIT) is the commonest cause of severe isolated thrombocytopenia in the foetus and newborn. In Cauc asians, 97% of NAIT are caused by HPA-1a or HPA- 5b alloantibodies. By combining CD40 activation and Epstein-Barr virus transformation of B cells isola ted from a woman with high titre of anti -HPA-5b alloan tibodies. F2H11 human monoclonal antibody is highly specific (does not bind to HPA5a) , and allows a r apid and accurate phenotyping of pregnant women as well as selection of blood donors. (Mérieux Y, Rigal D, Pin JJ, XVII th Regional Congress, International Society of Blood Transfusion, Madrid 2007 ; Guillot -Chene P, Lebecque S, Rigal D, Annales Pharmaceutiques Françaises, 06/2009, 67 (3) 182-6).
Synonyms human platelet antigen 5b
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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