CD49b (ITGA2) Human Monoclonal Antibody [Clone ID: B4F12]
CAT#: DDX9022P-100
CD49b (ITGA2) human monoclonal antibody, clone B4F12
Need it in bulk or conjugated?
Get a free quote
CNY 8,775.00
货期*
4周
规格
Specifications
Product Data | |
Clone Name | B4F12 |
Applications | ELISA, FC, IF |
Recommend Dilution | IF, ELISA, preferential detection of activated platelet by flow cytometry, platelet aggregation studies. Usage recommendation: *This monoclonal antibody may be used between 5-25μg/ml. *Optimal dilution should be determined by each laboratory for each application. *Coupled antibody: to maintain RT before use. |
Reactivity | Human |
Host | Human |
Clonality | Monoclonal |
Immunogen | CD40 activated and EBV immortalized human B lymphocytes |
Specificity | GPIa-IIa preferentially on acitvated platelets. |
Formulation | 100 μg in 200 μl / 50 μg in 100 μl Tris-NaCl pH 8 State: Purified |
Concentration | lot specific |
Purification | QMA Hyper D ion exchange chromatography |
Conjugation | Unconjugated |
Storage Condition | -20°C. KEEP CONTENTS STERILE: no preservative. Purified antibodies: avoid repeated freeze/thaw cycles. Coupled antibodies: glycerol protects from freezing. |
Gene Name | integrin subunit alpha 2 |
Database Link | |
Background | Neonatal AlloImmune Thrombocytopenia (NAIT) is the commonest cause of severe isolated thrombocytopenia in the foetus and newborn. In Caucasians, 97% of NAIT are caused by HPA-1a or HPA- 5b alloantibodies. B4F12 was isolated after combination of CD40 activation and Epstein-Barr virus transformation of B cells isolated from a woman with high titre of anti -HPA-5b alloantibodies. B4F12 human monoclonal antibody recognizes GPIa-IIa preferentially on activated human platelets (Mérieux Y, Rigal D, Pin JJ, XVIIth Regional Congress, International Society of Blood Transfusion, Madrid 2007 ; Guillot-Chene P, Lebecque S, Rigal D, Annales Pharmaceutiques Françaises, 06/2009, 67 (3) 182-6). |
Synonyms | Integrin alpha-2, ITGA-2, VLA-2 alpha, VLA2, GPIa, Collagen Receptor |
Reference Data |
Documents
Product Manuals |
FAQs |
SDS |
Resources
抗体相关资料 |
Customer
Reviews
Loading...