Chikungunya Human Monoclonal Antibody [Clone ID: E04C1.02]

Specifications

Product Data
Clone Name	E04C1.02
Applications	IF, Neutralize
Recommend Dilution	IF, Seroneutralization
Reactivity	Human
Host	Human
Clonality	Monoclonal
Specificity	Chikungunya virus
Formulation	Tris-NaCl, pH 8 State: Purified
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	- 20°C. KEEP CONTENTS STERILE: no preservative.  Purified antibodies: avoid repeated freeze/thaw cycles.
Background	Chikungunya virus was first isolated from the blood of a febrile patient in Tanzania in 1953, and has since been cited as the cause of numerous human epidemics in many areas of Africa and Asia and most recently in limited areas of Europe. Chikungunya virus is a member of the genus Alphavirus , in the family Togaviridae . Chikungunya fever is diagnosed based on symptoms , physical findings (e.g., joint swelling), laboratory testing , and the possibility of exposure to infected mosquitoes. There is no specific treatment for Chikungunya fever; care is based on symptoms. PBMC isolated from a Chikungunya infected patient was cultured in the CD40 system supplemented with an EBV viral suspension. Immortalized antibody - secreting B clones were obtained and screened for their neutralizing activity against several Chikungunya virus strains. Seroneutralization of other viruses such as Ross River virus and ONyong Nyong virus was found.
Reference Data

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