GM CSF (CSF2) Mouse Monoclonal Antibody [Clone ID: 429]

Specifications

Product Data
Clone Name	429
Applications	ELISA
Recommend Dilution	ELISA: This Biotin-conjugated monoclonal antibody can be used as a Tracer/Detection antibody in Sandwich ELISA applications for Human GM-CSF detection in combination with a Capture antibody Clone 59 (Cat.-No DM1014). Suggested Capture Coating Dose: ~0.3 µg/ml. Substrate: TMB. If the above suggested conditions are followed approximately 2 pg/ml of GM-CSF in serum/ plasma or medium can be detected with an assay range of 0-500 pg/ml.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant Human GM-CSF.
Specificity	This monoclonal antibody reacts with natural and recombinant human GM-CSF. Does not show any cross reaction with other human Cytokines or Growth Factors tested such as M-CSF, G-CSFR, IL-8, IL-16, IL1-beta, TGFbeta-1 and TNF-alpha.
Formulation	0.01M PBS, pH 7.0 ± 0.1 Label: Biotin State: Liquid purified IgG fraction Stabilizer: 1% Gelatin Preservative: 0.1% Proclin-300
Purification	Affinity Chromatography on Protein G
Conjugation	Biotin
Storage Condition	Upon receipt, store (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	colony stimulating factor 2
Database Link	Entrez Gene 1437 Human UniProt ID P04141
Background	The cytokine GM-CSF stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. Used in myeloid reconstitution following bone marrow transplant, bone marrow transplant engraftment failure or delay, mobilization and following transplantation of autologous peripheral blood progenitor cells, and following induction chemotherapy in older adults with acute myelogenous leukemia.
Synonyms	CSF2, GMCSF, Sargramostim, Molgramostin
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways	Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway

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