IL1 beta (IL1B) Mouse Monoclonal Antibody [Clone ID: S1H12]
CAT#: DM1019
IL1 beta (IL1B) mouse monoclonal antibody, clone S1H12, Purified
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CNY 7,337.00
货期*
4周
规格
Cited in 3 publications. |
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Specifications
Product Data | |
Clone Name | S1H12 |
Applications | ELISA, WB |
Recommend Dilution | ELISA. Western Blot: An antibody concentration of 20-100 ng/mL will allow visualization of 100 ng/lane of human IL-1β. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Purified recombinant human IL-1β |
Specificity | Reactive with natural and recombinant human IL-1β. Does not show any cross reaction with recombinant human IL-1α, recombinant murine IL-1α or IL-1β. |
Formulation | 0.01M PBS, pH 7.2 State: Purified State: Lyophilized purified IgG |
Reconstitution Method | Restore with double distillated water is recommended to adjust the final concentration to 1.00 mg/ml |
Purification | Protein G affinity purified |
Conjugation | Unconjugated |
Storage Condition | Store the antibody at -20°C. Avoid repeated freezing and thawing. |
Gene Name | interleukin 1 beta |
Database Link | |
Background | Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types, and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin1 alpha (IL1 alpha) and interleukin1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25% homology in their amino acid sequence. |
Synonyms | IL-1 beta, IL1B, IL1 beta, IL1F2, Catabolin |
Reference Data |
Citations (3)
The use of this Antibodies has been cited in the following citations: |
---|
Treponema pallidum promotes macrophage polarization and activates the NLRP3 inflammasome pathway to induce interleukin-1β production
,null,
BMC Immunology
,PubMed ID 30217146
[IL1B]
|
Duhuo Jisheng Decoction inhibits SDF-1-induced inflammation and matrix degradation in human degenerative nucleus pulposus cells in vitro through the CXCR4/NF-κB pathway
,null,
Acta Pharmacologica Sinica
,PubMed ID 29795361
[IL1B]
|
Functional proteomics revealed IL-1β amplifies TNF downstream protein signals in human synoviocytes in a TNF-independent manner.
,null,
Biochemical and biophysical research communications
,PubMed ID 24928389
[IL1B]
|
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