Mucin-16 / CA125 Mouse Monoclonal Antibody [Clone ID: OV185:1]

Specifications

Product Data
Clone Name	OV185:1
Applications	IHC
Recommend Dilution	Immunohistochemistry on paraffin embedded sections: diluted of 1:25-1:50 in an ABC method (30 minutes at room temperature) Positive Control: Ovarian carcinoma
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Partially purified human mucin fraction from a pool of cancer tissues of patients with epithelial ovarian cancer.
Specificity	This antibody reacts specifically with CA125 ovarian cancer antigen. Cellular Localization: Extracellular membrane
Formulation	10 mM citrate buffer, pH 6.0 State: Supernatant State: Supernatant, The antibody is supplied as a purified IgG fraction containing sodium azide as a preservative.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	mucin 16, cell surface associated
Database Link	Entrez Gene 94025 Human UniProt ID Q8WXI7
Background	Several studies have shown that CA125 is useful tumor marker for ovarian epithelial malignancies. However, CA125 has been described in other neoplasms such as seminal vesicle and anaplastic lymphomas.
Synonyms	MUC16, MUC-16, CA-125, CA 125
Reference Data

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