Granzyme K (GZMK) Mouse Monoclonal Antibody [Clone ID: GM24C3]

CAT#: DM1209

Granzyme K (GZMK) mouse monoclonal antibody, clone GM24C3, Purified



Need it in bulk or conjugated?
Get a free quote

CNY 5,660.00


货期*
5周

规格
    • 100 ug

Cited in 2 publications.

Product images

Specifications

Product Data
Clone Name GM24C3
Applications ELISA, FC
Recommend Dilution Flow Cytometry: 1.2 µg/106 cells.
ELISA: 1/200-1/400.
Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen GM24C3 was generated by genetic immunisation of BALB/c mice with an immunisation vector containing the Granzyme K cDNA
Specificity This antibody recognizes Granzyme K (GZMK).
Formulation PBS, pH 7.2 without preservatives
State: Purified
State: Liquid purified IgG fraction.
Concentration lot specific
Purification Affinity Chromatography on Protein G
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name granzyme K
Background Granzyme K (GrK) belongs to a family of trypsin-like serine proteases localised in the cytotoxic granules of activated T cells and NK cells. It encodes a 28 kDa serine protease whose gene is located on chromosome 5q11-12 close to the granzyme A-encoding gene. Like granzyme A, it has a trypsin-like specifity cleaving at the basic residues arginine and lysine. Granzyme K triggers rapid cell death independently of caspase activation with single-stranded DNA nicks and is primarily expressed in thymus, lung, spleen and peripheral blood leukocytes.
Synonyms Granzyme-3, NK-tryptase-2, Fragmentin-3, TRYP2, NK-Tryp-2
Note Selection: based on recognition of the complete native protein expressed on transfected mammalian cells.
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (2)

Customer Reviews 
Loading...