Prostatic Acid Phosphatase (ACPP) Mouse Monoclonal Antibody [Clone ID: LT-3D1]

Specifications

Product Data
Clone Name	LT-3D1
Applications	ELISA, FC, WB
Recommend Dilution	Flow cytometry: 1.2 µg/10e6 cells. Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400. ELISA (detection): With clone LT-6C11-A1 as capture antibody.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Genetic immunisation with cDNA encoding Human PAP.
Specificity	Recognizes Prostatic Acid Phosphatase PAP (PAcP, ACPP).
Formulation	Phosphate buffered saline, pH 7.2 State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	acid phosphatase, prostate
Database Link	Entrez Gene 55 Human UniProt ID P15309
Background	Human prostatic acid phosphatase (PAP) is a non-specific phosphomonoesterase, synthesised and secreted into seminal plasma under androgenic control. Human PAP is a 100 kDa glycoprotein containing two subunits of approximately 50 kDa each (1,2). It catalyses the dephosphorylation of organic monophosphate esters, demonstrating optimum activity at an acid pH. Produced by the prostatic epithelium, serum levels of PAP are very low in healthy individuals, but are often elevated in malignant and benign prostatic disease while it has been used as a marker of diagnosis and therapy control of cancer of the prostate gland (3).
Synonyms	Prostate acid phosphatase, PAP, ACP3, PSAP
Reference Data
Protein Families	Druggable Genome, Phosphatase, Transmembrane
Protein Pathways	Riboflavin metabolism

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.